Role of Cardiac Magnetic Resonance in the Diagnosis of Cardiac Amyloidosis
نویسندگان
چکیده
Cardiac amyloidosis (CA) is characterized by progressive pathological deposition of amyloid fibrils in the myocardial interstitium, resulting ultimately restrictive cardiomyopathy. The accumulating heart are most commonly misfolded immunoglobulin light chains (in case AL amyloidosis) or transthyretin (ATTR), latter being either wild-type variant conformation.
منابع مشابه
Cardiac Amyloidosis: The Role of Magnetic Resonance Imaging
Amyloidosis, an infiltrative disease characterized by deposition of high molecular weight insoluble protein has a low detection rate and poor prognosis with congestive heart failure being the most common cause of death. Although definitive diagnosis is based on endomyocardial biopsy, this is rarely performed due to procedural risk and sampling error. Traditional non-invasive imaging, such as tr...
متن کاملMagnetic resonance imaging in cardiac amyloidosis.
The amyloidoses are a group of uncommon systemic diseases characterized by the extracellular deposition of pathologic insoluble amyloid protein in organs and tissues. The are 4 main types of amyloidosis: primary (AL, the most prevalent type), familial, secondary, and senile. Each of them has its own physiopathology, distinctive features, and variable cardiac involvement. The symptoms of cardiac...
متن کاملCardiovascular Magnetic Resonance in Cardiac Amyloidosis
Background—Cardiac amyloidosis can be diagnostically challenging. Cardiovascular magnetic resonance (CMR) can assess abnormal myocardial interstitium. Methods and Results—Late gadolinium enhancement CMR was performed in 30 patients with cardiac amyloidosis. In 22 of these, myocardial gadolinium kinetics with T1 mapping was compared with that in 16 hypertensive controls. One patient had CMR and ...
متن کاملTypical cardiac magnetic resonance imaging findings of cardiac amyloidosis.
We report the case of a 62-year-old man who presented with shortness of breath, lower extremity edema and clinical signs of congestive heart failure. Transthoracic echocardiography demonstrated concentric left ventricular hypertrophy with severe diastolic dysfunction and biatrial enlargement. After aggressive diuresis and clinical improvement, a cardiac magnetic resonance imaging (CMR) examinat...
متن کاملCardiovascular magnetic resonance in cardiac amyloidosis.
BACKGROUND Cardiac amyloidosis can be diagnostically challenging. Cardiovascular magnetic resonance (CMR) can assess abnormal myocardial interstitium. METHODS AND RESULTS Late gadolinium enhancement CMR was performed in 30 patients with cardiac amyloidosis. In 22 of these, myocardial gadolinium kinetics with T1 mapping was compared with that in 16 hypertensive controls. One patient had CMR an...
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ژورنال
عنوان ژورنال: Journal of cardiac critical care TSS
سال: 2021
ISSN: ['2457-0206', '2456-9224']
DOI: https://doi.org/10.1055/s-0042-1743394